CrossFit | The Diet-Heart Hypothesis, Part 4

The Diet-Heart Hypothesis, Part 4: Impact of the DHH

ByDr. Malcolm KendrickSeptember 5, 2019

The world’s first major dietary guidelines were published in 1977 in the U.S. and were primarily designed to help prevent cardiovascular disease (CVD). Gerald Oppenheimer and I. Daniel Benrubi described this as an “extraordinary act”:

[E]nough of a consensus existed among cardiovascular epidemiologists and nutritionists and within the American Heart Association that the important Senate Select Committee on Nutrition and Human Needs (hereafter, “the committee”) used the diet-heart association to perform an extraordinary act: advocate dietary goals for the American population. This was “the first comprehensive statement by any branch of the Federal Government on risk factors [for chronic disease] in the American diet.” (1, my emphasis)

A first important question to answer is whether the guidelines have had the hoped for effect on the consumption of different dietary macronutrients. The available data suggest this had been the case, as outlined in the paper “Statistical Review of U.S. Macronutrient Consumption Data, 1965–2011”:

  • Americans have been adhering to federal dietary guidelines for the past 40y
  • Fat consumption by US adults decreased from 45% to 34% between 1965 and 2011.
  • Carbohydrate consumption increased from 39% to 51% over this same period. (2)

The question that follows from this is whether these changes resulted in a positive or negative effect on health, specifically heart disease/cardiovascular disease. It is difficult to answer this question with absolute certainty. Over a period of several decades, many different factors other than the intake of various macronutrients have changed significantly.

For example, in the U.S., the rate of cigarette smoking has decreased considerably, from 42% in 1965 to 14% today (3). The rate of smoking has also fallen in most other Western countries during the same time period.

In addition, air pollution has improved, and air pollution is a major risk factor for cardiovascular and cardiorespiratory diseases (4).

Another factor is the removal of lead from fuel. In the U.S. alone, around 200,000 tons of lead entered the atmosphere each year from car exhaust. Studies have suggested that low-level lead poisoning may have caused as many deaths from cardiovascular disease as smoking:

New estimates suggest that 256,000 premature deaths from cardiovascular disease — including 185,000 deaths from ischemic heart disease — in the United States may be linked to historical lead exposure in middle-aged and older adults (people currently aged 44 years or over). (5)

Running parallel to the reduced exposure to several harmful agents, there have been many advances in medical treatments that have reduced the mortality from heart disease. For example, the death rate from heart attacks with hospital admission has gone down from around 40% to 8%.

All of this means the mortality rate from cardiovascular disease and, specifically, coronary heart disease, has been decreasing steadily in the U.S. for many years, starting in the early 1960s.

Clearly, this fall began many years before the dietary guidelines were introduced and has continued since (Figure 1). The rate of decrease appears to have been unaffected by the 1977 guidelines. More recently, the decline has leveled off (6).

In fact, in 2017, improvements in cardiovascular disease halted completely. As Sherry Murphy et al. explain:

With a slight decrease in deaths from heart disease in 2017 and a slight increase in deaths from stroke, this lack of any major movement in these areas has been a trend we’ve seen the last couple of years. (7)

In fact, the long-term improvement in CVD mortality has not only come to a halt, it may be reversing. In the U.K., deaths from heart disease increased in 2018 and mainly have been attributed to increases in obesity and diabetes. A similar trend has also been noted in the U.S., where the rate of diabetes has increased significantly (8).

It is difficult to disentangle causality when so many variables are changing simultaneously. However, it seems likely that the epidemic of obesity and diabetes is now negatively impacting the other positive factors that have led to previous long-term improvements (9).

This raises the question, can it be established whether the changes in dietary intake have been a significant factor in the rise in obesity and diabetes in the U.S. and other Westernized countries? It is certainly true that there has been an increase in carbohydrate consumption (Figure 2), and several researchers have suggested this may have been a factor in driving an increase in both obesity and diabetes.

Evan Cohen et al. write:

Since 1971, the shift in macronutrient share from fat to carbohydrate is primarily due to an increase in absolute consumption of carbohydrate as opposed to a change in total fat consumption. General adherence to recommendations to reduce fat consumption has coincided with a substantial increase in obesity. (2)

The suggestion here is that, while the dietary guidelines led to the hoped for increase in carbohydrate consumption along with a relative reduction in fat consumption, this may have led to an increase in obesity and diabetes, which in turn has led to recent increases in the rate of CVD.


  • There is a high correlation between the change in diet and the rise of obesity.
  • The percentage of overweight adults has increased from 42% to 66% since 1971. (2)

It could therefore be argued that the dietary guidelines have, at least in part, been damaging rather than beneficial. It is possible they could be behind the rise in obesity and diabetes in the U.S. and many other countries, which in turn is an important causal factor in the recent reversal in long-term improvements in morbidity and mortality from CVD. To put it more starkly, a strong possibility exists that the dietary guidelines have increased rather than reduced the risk of CVD.

Additional Reading

KendrickMalcolm Kendrick is a family practitioner working near Manchester in England. He has a special interest in cardiovascular disease, what causes it, and what may prevent it. He has written three books: The Great Cholesterol ConDoctoring Data, and A Statin Nation. He has authored several papers in this area and lectures on the subject around the world. He also has a blog,, which stimulates lively debate on a number of different areas of medicine, mainly heart disease.

He is a member of THINCS (The International Network of Cholesterol Sceptics), which is a network of doctors and scientists who believe that cholesterol is not the main underlying cause of heart disease. He remains a proud Scotsman, whisky drinker, and failed fitness fanatic who loves a good scientific debate — in the bar.

He is a member of THINCS (The International Network of Cholesterol Sceptics), which is a network of doctors and scientists who believe that cholesterol is not the main underlying cause of heart disease. He remains a proud Scotsman, whisky drinker, and failed fitness fanatic who loves a good scientific debate — in the bar.


  1. Oppenheimer GM, Benrubi ID. McGovern’s Senate Select Committee on Nutrition and Human Needs Versus the: Meat Industry on the Diet-Heart Question (1976–1977). . 104.1(2014): 59–69.
  2. Cohen E, et al. Statistical review of US macronutrient consumption data, 1965–2011: Americans have been following dietary guidelines, coincident with the rise in obesity. Nutrition. 31.5(2015): 727-732.
  3. LaVito A. CDC says smoking rates fall to low in US. 8 Nov. 2018. Accessed Aug. 28, 2019. Available here.
  4. Byeong-Jae L, Bumseok K, and Lee K. Air pollution exposure and cardiovascular disease. Toxicol. Res. 30.2(2014): 71-5.
  5. Historical lead exposure may be linked to 256,000 premature deaths from cardiovascular disease in adults in the United States each year. 12 March 2018. Accessed Aug. 28, 2019. Available here.
  6. Achievements in public health, 1900-1999. 6 Aug. 1999. Accessed Aug. 28, 2019. Available here.
  7. Murphy SL, et al. CDC: Heart disease, cancer leading causes of death in 2017. NCHS Data Brief. 328(2018): 1-8.
  8. Bodkin H. Heart disease deaths in under 75’s going up for the first time in 50 years. 13 May 2019. Accessed Aug. 28, 2019. Available here.
  9. Bhupathiraju SN, and Hu FB. Epidemiology of obesity and diabetes and their cardiovascular complications. Circulation Res. 118(2016): 1723-1735.

Comments on The Diet-Heart Hypothesis, Part 4


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Joe Butler
September 6th, 2019 at 6:28 pm
Commented on: The Diet-Heart Hypothesis, Part 4

Read back from part 1. Good physiology review. Enjoyed the history involved in the evolution of the dietary guidelines.

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