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"Peer review is at the heart of the processes of not just medical journals but of all science," writes Richard Smith, former editor of the BMJ. In this excerpt from his book, The Trouble With Medical Journals, Smith argues "peer review is a flawed process full of easily identified defects with little evidence that it works." He proposes a few ways the system may be improved.

“Clinical trial data behind drug dose recommendations for elevated cholesterol and chronic obstructive pulmonary disease illustrate how larger doses may not be worth the extra costs for many types of patients, according to an Oregon State University College of Pharmacy researcher.”

A 2020 review finds more than three-quarters of those serving on the boards of major medical organizations have received funding from industry. This indication of pervasive conflicts of interest among the leadership of leading U.S. medical organizations reveals the level of industry influence may be substantial.

"A cardiologist has blamed the food industry for ‘normalising’ ultra-processed junk food as more evidence emerges suggesting poor diet is the root cause behind increased mortality from Covid-19."

In the previous column, Dr. Timothy Noakes listed the sequence of events that were critical in directing the global acceptance of Ancel Keys’ diet-heart and lipid hypotheses. In this column, he investigates the relevant events that unfolded between 1910 and 1948 and discusses Dr. Vladimir Subbotin’s alternative hypothesis for coronary atherosclerosis.

Twelve weeks on a higher-quality diet led to significant improvements in measures of major depression in this small randomized controlled trial.

Dr. Georgia Ede reviews the 2017 SMILES trial, noting it supports “the common-sense notion that the human brain cares deeply about what we eat.” She concludes, “Clearly the most powerful way to fundamentally change your brain chemistry is through food, because that’s where the brain chemicals come from in the first place.”

Science, a branch of human knowledge, is not an obscure occupation safely ignored by the intellectually lazy or those who lack interest in its study. It is impossible to escape its realities and consequences.

CrossFit, Inc. presents CrossFit Health Education, a program that provides continuing education and professional development opportunities for physicians, health-care professionals, and trainers. Membership in the program is also open to anyone interested in furthering their understanding of medical science, human health, and performance via access to world-class experts and educational content.

COVID-19 severity among well-controlled diabetics differs little from that in nondiabetics, but those with poorly controlled blood glucose have substantially increased risk of severe disease and mortality.

This article, the second installment in a four-part series on meal timing, discusses the physiological effects of various time-restricted eating patterns. Series author Tyler Hass reviews the scientific literature on the subject and calls for more studies on a wider variety of populations using different intermittent fasting strategies, better quality food, and more effective exercise protocols.

As politicians justify lockdowns to prevent COVID-19 deaths, the unintended consequences must be considered. Unemployment and missed medical treatments contribute to an estimated 700,000 years of life lost for every month of lockdown. This opinion piece argues for a careful return to normalcy.

Science is the objective branch of knowledge. Yet objectivity is not an absolute, and it is not guaranteed simply by supplying measurements. Objectivity lies in scientific models and their predictive powers. Objectivity is not a discrete entity, either present or absent, but is a continuously valued parameter.

In this 2020 editorial, the editor-in-chief of Molecular Brain finds a significant share of authors are unable or unwilling to provide the raw data to substantiate their results, raising questions regarding the potential for unchecked fraud and error.

A simple understanding of how things are built forms the core of our knowledge of how to change their structure to improve their function. The physiological processes inducing and supporting muscle contraction are numerous, diverse, and important to know.