Professor Richard Feinman delves further into the underlying biochemical processes that regulate energy metabolism. He explains how cellular structure alters in a cancerous state, focusing in particular on how cancer disrupts the entry of pyruvate into the mitochondrion. Several cancers, such as squamous cell carcinomas of the head and neck, have been shown to inhibit pyruvate dehydrogenase regulation. Feinman observes that looking at pyruvate reveals several of the ways in which the normal link between glycolysis and respiration becomes disturbed in a cancerous state. It remains to be discovered whether any of these disturbances can be targeted for therapy.
Read MoreCancer and Metabolism, Part 23 rounds for time of:
50 squats
7 strict muscle-ups
10 hang power cleans
♀ 95 lb. ♂ 135 lb.
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