A model is a container of Modern Science. Science is a branch of knowledge, in particular objective knowledge. It possesses objectivity by expressing relationships, AKA experiments, only among facts, where a fact is an observation reduced to measurements and compared with standards. A model is an expression of an arrangement of facts that exposes, or seeks to expose, a pattern among variables or parameters expressed as records of facts, identifying candidate variables as independent and others as dependent variables, or, more generally, as Causes and Effects.

James DiNicolantonio and James O’Keefe summarize evidence that omega-6 fatty acids promote inflammation, while omega-3s are anti-inflammatory. Seed oils high in linoleic acid contribute to atherosclerotic risk via impacts on inflammation, oxidative stress, and other downstream effects; conversely, omega-3s suppress some of these same pro-inflammatory mechanisms.