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Tuesday

200324

Workout of the Day

93

5 2-minute rounds of:

20 dumbbell box step-ups
Max reps of dumbbell push presses

Rest 2 minutes between rounds

♀ 35-lb. DBs and 16-in. box
♂ 50-lb. DBs and 20-in. box

Post push press reps completed each round to comments.

Comments on Targeting Glucose Metabolism to Enhance Immunotherapy: Emerging Evidence on Intermittent Fasting and Calorie Restriction Mimetics

3 Comments

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Mary Dan Eades
March 25th, 2020 at 11:17 pm
Commented on: Targeting Glucose Metabolism to Enhance Immunotherapy: Emerging Evidence on Intermittent Fasting and Calorie Restriction Mimetics

Certainly, basic biochemistry would suggest that starving glucose-dependent cancer cells of their one fuel source should render them more vulnerable and make them more easily killed by things that will kill them. And as long as they don't 'learn' to use another fuel, that works well. Some of them, however, do learn to utilize other fuels over time. For an evolutionary take on cancer treatment, this talk by Dr. Dawn Lemanne is really interesting and offers more fuel for thought.

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Michael Suhadolnik
March 24th, 2020 at 9:08 am
Commented on: Targeting Glucose Metabolism to Enhance Immunotherapy: Emerging Evidence on Intermittent Fasting and Calorie Restriction Mimetics

We will never be on first base until we investigate the impact of processed stuff we label as food.

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jr Wild
March 24th, 2020 at 8:12 am
Commented on: Targeting Glucose Metabolism to Enhance Immunotherapy: Emerging Evidence on Intermittent Fasting and Calorie Restriction Mimetics

"the lack of human trial data means there is not currently evidence to support the direct claim that metabolic therapies can improve cancer outcomes."


There is a Turkish hospital doing exactly this and publishing their results. Several small studies, which are used as "marketing" I believe. With that in mind, their results in vivo are interesting. They have read their Warburg, Seyfried, D'Agostini, Feinman I guess. The adjunct measures include ketogenic diet, hyberbaric treatment, artificial glucose lowering berofe "usual care" treatment, no sauna but local heat treatment, some oral and infusion additives... So they have changed quite a few variables at the same time. Targeting glucose metabolism is big part of this.


https://chemothermia.com/news-research/lung-cancer-results-published/


So I do not know how watertight this is, but they try (and charge) and test and publish. Judge yourself...

JR

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